摘 要
本實驗藉由固相微萃取的概念自行設計出一種高分子薄膜，其功能相同於固相微萃取的吸附靜相，增加高分子薄膜的厚度，提高萃取分析物的量，降低偵測極限，實驗中選取聚氧矽烷（PDMS）作為高分子薄膜的基材，其特性具有良好的熱穩定性、不易被氧化等特性，商業應用相當廣泛舉凡合成機油、接著劑、絕緣劑、或是表面處理等，在分析技術的應用方面在商業化SPME上也採用PDMS作為萃取非極性化合物的靜相。
在實驗中分別選取了兩種不同結構的PDMS分子一為長鏈狀的高分子，其次為經由交聯反應而成為網狀結構的分子，並以玻璃載體作為薄膜塗佈的基材，將兩種高分子物質分別塗佈在玻璃載體上作為靜相吸附的材質，並在實驗的過程中對兩種不同聚合程度之PDMS高分子，探討影響萃取分析物效率的各項參數如萃取溫度、萃取時間、薄膜厚度，由於塗佈上高分子的玻璃載體並無法配合層析儀的注射埠，而特別設計了一套自動化熱脫附進樣系統利於分析樣品的使用，在連續分析7個相同濃度的BTEX樣品，再現性約達 RSD 5 % 以下，並在最後與商業化的固相微萃取裝置比較之下，發現其在FID的感度表現下也較商業化SPME塗佈上100μm PDMS的纖維高出數十至百倍。

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參考文獻
[1] Silgoner, I., Rosenberg, E., Grasserbauer (1997) Manfred. “Determination of volatile organic compounds in water by purge-and-trap gas chromatography coupled to atomic emission detection” J. Chromatogr. A., pp. 259-270.
[2] Bruno, K. (1999) “Review headspace sampling with capillary column” J. Chromatogr. A, 842, 163-205.
[3] Harrison, I., Leader, R.U., Higgo, J.J.W., Tjell, J.C. (1994) “Determination of organic pollutants in small samples of groundwaters by liquid-liquid extraction and capillary gas chromatography” J. Chromatogr. A, 688, 181-188.
[4] Simpson, N.J.K. (2000) “Solid-phase extraction principle, techniques, and application” Marcel Dekker Inc., New York Basel.
[5] Pawliszyn, J. (1999) “Applications of Solid phase microextraction” Royal Society Of Chemistry.
[6] Pawliszyn, J. (1997) “Solid Phase Microextraction Theory and Practice.” Wiley-VCH.
[7] Hawthone, S., Miller, D., Arthur, C., Pawliszyn, J. (1992) “Solventless determination of caffeine in beverages using SPME with fused silica fibers” J. Chromatogr., 603, 185-191.
[8] Wasowicz, E., Kaminski, E., Jelen, H., Wlazly, K. (1998) “Alcohols and ester in beer : comparison with static headspace method” J. Agric. Food Chem. 46, (4), 1469-1473.
[9] Singer, K., Wenz, B., Seefeld, V., Seeper, U. (1995) “Determination of drug of abuse using SPME” (German) Lab-Med., 18, (2), 112-118.
[10] Choudhury, T., Gerhardt, K., Mawhinney, T. (1996) “Solid phase microextraction of nitrogen-and phosphorus-containing pesticides from water and GC analysis” Environ. Sci. Technol., 30, 3259-3265.
[11] Arthur, C., Pratt, K.,Belardi, R., Motagh, S., Pawliszyn, J. (1992) “Environmental analysis of organic compounds in water use solid phase microextraction” J. High Res. Chromatogr. 15, 741-744.
[12] Migdic, C., Pawliszyn, J. (1996) “Analysis of organochlorine pesticides by SPME” J. Chromatogr. A, 723, 111-112.
[13] Chen, J., Pawliszyn, J., (1995) “Solid phase microextraction coupled to HPLC”. Anal. Chem., 67, 2530-2563.
[14] Schnoor, J. L. (1996) ” Environmental Modeling- Fate and transport of Pollutants in water , Air and Solid” John Woley & Sons Inc.
[15] Ligor, M., Buszewski, B. (1997) “Solid-phase microextraction as method for preparing environmental samples “ J. Environ. Studies, 6, 5.
[16] Benijts, T., Vercammen, J., Dams, R., Tuan, H.P., Lambert, W., Sanddra, P. (2000) “Stir bar sorptive extraction-thermal desorption-capillary gas chromatography-mass spectrometry applied to the analysis of polychroinated biphenyls in human sperm” J. Chromatogr. B, 755, 137-142.
[17] 陳韋立,（2000）大氣及水樣中揮發性有機氣體自動化分析技術之建立與應用, 中央大學碩士論文。
[18] 彭耀寰,（1995）高分子材料, 大中國圖書公司。
[19] 許麗秋,（2000）尿中BTEX與其代謝物關係之研究, 中國醫藥學院碩士論文。
[20] Thomas, T., C., Kendrick, T.C.(1969) “Thermal analysis of polydimethylsiloxanes, Ⅰthermal degradation in controlled atmospheres” J. Polymer Science , A-2, 7, 537-549.
[21] Menedz, J., C, .E., Sanchez, M., L, .F., Uria, J., E., S., Martinez, E., F, San-Medel, A. (2000) “Static,solid-phase microextraction and headspace solid-phace microextraction for BTEX determination in aqueous sample by gas chromatography” Analytica Chimica Acta, 415, 9-20.
[22] Chong, S., L., Wang, D., Hayes, J., D., Wilhite, B., W., Malik, A. (1997) “Sol-gel coating technology for the preparation solid phase microextraction fibers of enhanced thermal stability” Anal. Chem., 69, 3889-3898,