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研究生: 吳維軒
Wei-Hsuan Wu
論文名稱: 獨立成份分析法於即時心電訊號萃取應用
The measurement and application of Independent Component Analysis in instant ECG
指導教授: 李柏磊
Po-Lei Lee
口試委員:
學位類別: 碩士
Master
系所名稱: 資訊電機學院 - 電機工程學系
Department of Electrical Engineering
畢業學年度: 96
語文別: 中文
論文頁數: 67
中文關鍵詞: 肌電訊號心電圖獨立成份分析法
外文關鍵詞: Independent Component Analysis(ICA), Electrocardiogram (ECG), Electromyography (EMG)
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  • 以往國人對於醫療的認知還是停留在醫院內醫生必須直接面對病人做診斷,但近年來,國人對於醫療與人性化的概念有了更深一層的認識,並且將這兩者做了結合,所以對病人而言,他們的生活空間並不僅僅被侷限在醫院內,更可以是在家中或是戶外,而這些進步大大的改善了病人的生活方式,但此進步必須建立於遠端醫療與居家看護系統的發展上,有鑑於此,最重要的就是要精確的知道病人的現在身體狀況以供遠端醫院的醫生做即時診斷,以患有心血管疾病的人來說,要知道他的心臟狀況,就必須靠著心電圖(Electrocardiogram,ECG)讓醫生做判斷,但是由於人體在活動中會產生許多訊號,例如:肌電訊號(Electromyography,EMG)等,甚至機器等會帶有電力線的雜訊干擾,所以要如何從量測到的訊號中正確的分離出ECG訊號或其他生理訊號則是此篇文章的重點。
    獨立成份分析法(Independent Component Analysis,ICA)[1]最初發展出來約在1990年,在這裡我們使用獨立成份分析法即時的對於所量測到的訊號作來源訊號的分離與重建,量測訊號取得我們使用六個電極貼片分別貼在兩隻手前臂前端內側,期間我們嘗試做簡單的擺動手臂,拿東西等一些動作,然後使用獨立成份分析法去作即時分離我們所量測到的訊號,結果我們成功的分離出正確的ECG訊號,相信此舉對於遠端醫療與居家看護系統的發展相信能提供一大助力。


    With the developments of advanced medical instruments in recent years, the remote medicine and homecare system have been recognized as a new trend in the interaction between patients and doctors. This trend changes the life style of care medicine. Patients can use advanced nursing systems to record their physiological data at home and transmit these data to hospital network for necessarily monitoring. Nevertheless, these achievements require the novel developments of medical instruments, especially the noise-proof performance of these instruments.
    In this study, we aim to develop an Independent Component Analysis (ICA)-based ECG care system. ICA is a multi-variable technique which has been validated as a powerful tool for separating different signals according to their distinct statistical distributions. With the benefit of ICA, physiological and environmental ECG-unrelated noise can be removed so that the ECG signals can be extracted in low signal-to-noise (SNR) situation, even during uses’s limb movements. In order to validate the performance of the proposed ICA-based system, we attached six ECG electrodes (three on left hand and the other three on right hand) to extract the surface ECG of a user. ECG-unrelated noise and physiological signals, such as 60 Hz electricity noise, low frequency drifts and electromyogram contaminations can be identified and removed. Currently, we have implemented the ICA-based ECG care system on Labview platform for real-time processing. Further developments are required to realize the technique using dsPIC microprocessor for portable homecare purposes..

    目錄 中文摘要 I Abstract II 致謝 IV 目錄 V 圖目錄 VIII 表目錄 XIII 第一章 緒論 1 1.1前言 1 1.2相關研究於生理訊號文獻回顧 2 1.3研究動機 2 1.4研究目的 3 1.5研究方法 3 1.6論文架構 4 第二章 心電圖原理介紹 5 2.1生理訊號簡介 5 2.2心電圖簡介 5 2.2.1心電圖來源 6 2.2.2向量與導程的概念 7 2.2.3十二導程 7 2.3心電圖功能 9 第三章 研究理論與方法 10 3.1 引言 10 3.2 獨立成份分析法原理簡介 10 3.3 訊號原理簡介 13 3.3.1 峰態(kurtosis) 14 3.3.2 熵(entropy) 15 3.4 獨立成份分析法演算流程 17 3.4.1 第一部分:資料的前置處理 18 3.4.2 第二部份: Fixed-point algorithm using kurtosis 20 3.4.3 第三部份:重建來源訊號的大小 24 第四章 實驗原理與流程 25 4.1實驗說明 25 4.2 實驗架構 26 4.2.1硬體架構 26 4.2.2軟體架構 28 第五章 實驗結果 35 5.1模擬混合訊號的分離 35 5.2實驗前言 37 5.2.1即時訊號分離系統-身體放鬆 38 5.2.2即時訊號分離系統-手臂動作 42 5.2.3即時訊號分離系統-手臂用力 46 5.2.4即時訊號分離系統-電力線雜訊增強 51 5.2.5即時訊號分離系統-走路 55 5.2.6即時訊號分離系統-肢體碰觸 59 第六章 結論 64 參考文獻 66

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