長期以來B型肝炎、肝硬化與肝癌威脅著台灣青壯人口的身體健康，導致台灣勞動族群受此慢性疾病所苦，拖累個人的經濟表現，但健康卻是發展個人經濟行為的重要資本，完整的公衛政策可望提升民眾的健康水準、促進人力資本的累積。台灣政府於1984與1986年相繼施行B型肝炎疫苗的接種計畫，迄今已歷經30年之久，諸多文獻詳載與B型肝炎疫苗相關的醫學研究以及成本效益分析，證實疫苗政策可降低新生兒受到母體垂直感染以及未來水平感染的機率，同時確定慢性B型肝炎最嚴重的年齡層為30歲以後，使本文可找出適當的觀察樣本進行後續分析。本文資料來源為衛福部全民健保資料庫與主計總處之2010人口普查，運用斷點迴歸模型設計，將疫苗政策視為外生變因，並且賦予其政策虛擬變數，使男性與女性分開估計，實證B型肝炎疫苗對薪資水準的顯著影響，結果顯示無論是男性或女性，疫苗對於薪資皆為正向影響，1986年的政策效果比起1984年更為顯著，若於1986年接種過B肝疫苗，男性的薪資水準會提高1.07%、女性則為0.79%，除此之外，我們希望薪資水準的變化只單純受疫苗政策外生變動而影響，額外估計疫苗政策對教育水準之影響。最後證明男性薪資水準是因疫苗政策影響，不會受到教育因素的干擾，但女性卻有部分受到影響。

This literature proves the causal relationship between Hepatitis B vaccination and human capital. Hepatitis B virus (HBV) infection is one of the common reasons why some Taiwanese have chronic liver diseases, cirrhosis and hepatocellular carcinoma. Those chronic diseases threatened health level of Taiwanese young people, decreasing the human capital. Generally speaking, if the young are chronically infected with the HBV, hepatitis B will seriously interfere with economic activities in middle age. A nationwide program of hepatitis B vaccination has implemented in July 1984. In first two years, Newborns of HBsAg-positive mothers alone were vaccinated against HBV. After two years, all newborns have vaccinated in 1986. Numermous studies related with two programs revealed that prevalence of HBsAg was declining from 1984 until now. Because many epidemiology researches incidated the most severe phase of hepatitis B is the person whose age more than 30 years old, which makes me understand who are the samples of my article. The data resource came from Ministry of Health and Welfare, population and housing census 2010. I separated two genders in my data bases using Regression-Discontinuity Design to estimate causal relationships. Thus we exploited a dummy variable which represent program of hepatitis B vaccination and regarded monthly salary as independent variable. Whatever gender we estimated, our results suggest that both 1984 and 1986 programs are positive effect on monthly salary; also, program 1986 is more significant than 1984. Further, when Male had received hepatitis B vaccination in 1986, monthly salary would increase 1.07 percent. Otherwise, female who received hepatitis B vaccination in 1986 would raise to 0.79 persent. We hoped the variation of salary was only exogenously affected by hepatitis B vaccination, because we didn’t want the causal relationship to have endogeneity problems. Finally, we examined wheather the monthly salary was affected by education.

中文文獻：
1.劉俊人(2011)， B型肝炎‧治療&疫苗，健康世界：特別報導，民國100年。
2.許須美(1998)，台灣B型肝炎疫苗史，行政院衛生署：疫情報導，民國87年。
3.楊玉齡，羅時成，肝炎聖戰：台灣公共衛生史上的大勝利，民國88年。
4.顏哲傑，陳秀熙，楊淑兒 (2001)，「疫苗接種之一般化成本效益模式」，行政院衛生署疾病管制局自行研究計畫，計畫編號：DOH90-DC-2022。
5.行政院衛生署疾病管制局，臺灣兒科醫學會，臺灣感染症醫學會(2013)，感染與疫苗，行政院衛生署疾病管制局出版。
6.秦雪征，庄 晨，楊汝岱(2015)，「計畫生育提高了人口質量嗎？基於斷點迴歸設計（RDD）的研究」，北京大學經濟學院工作論文，編號：C-2015-001。
7.葉俊佑(2013)，「為錢賣子宮？子宮切除的道德風險」，國立臺灣大學社會科學院經濟學系在職專班碩士論文。
英文文獻：
1. Chan, CY., Lee,SD., Lo,KJ.(2004),“Legend of hepatitis B vaccination: The Taiwan experience.” Journal of Gastroenterology and Hepatology,19: 121-126
2. Zanetti, Alessandro R., Pierre V. Damme and Daniel Shouva.(2008), “The global impact of vaccination against hepatitis B: A historical overview” Vaccine,26: 6266–6273
3. Chen, CJ., Wang, LY., Yu,MW.(2000) “Epidemiology of hepatitis B virus infection in the Asia–Pacific region. ” Journal of Gastroenterology and Hepatology,15(2): E3–E6
4. Beasley, RP., Hwang,LY., Lin,CC., Chien,SC.“Hepatocellular carcinoma and HBV: a prospective study of 22,707 men in Taiwan. ” Journal of Lancet, 1981(2): 1129–33.
5. Chien, YC., Jan,CF. Kuo,HS. and Chen,CJ.(2006) “Nationwide Hepatitis B Vaccination Program in Taiwan: Effectiveness in the 20 Years After It Was Launched” Epidemiol Reviews, 2006(28):126–135
6. Lo,KJ., Tsai,YT., Lee,SD., Yeh,CL., Wang,JY., Chiang,BN., Wu,TC., Yeh,PS., Goudeau A , Coursaget P.(1985)“Combined passive and active immunization for interruption of perinatal transmission of hepatitis B virus in Taiwan. ”Journal of Gastroenterology and Hepatology Hepato-gastroenterology, 32(2):65-68
7. Ni,YH., Chang,MH., Wu,JF., Hsu,HY., Chen,HL., Chen,DS.(2012) “Minimization of hepatitis B infection by a 25-year universal vaccination program” Journal of Hepatology, 2012(57):730–73
8. Chiang, CJ., Yang,YW., You,SL., Lai,MS., Chen,CJ.“Thirty-Year Outcomes of the National Hepatitis B Immunization Program in Taiwan”(2013) JAMA, 310(9)：974-976
9. Szucs,Thomas.(2000) “Cost benefits of vaccination programmes” Vaccine ,18 (2000)：S49-S51
10. Hsu, HM., Lu,CF., Lee,SC. Lin,SR., and Chen,DS. (1999) “Seroepidemiologic Survey for Hepatitis B Virus Infection in Taiwan: The Effect of Hepatitis B Mass Immunization”Journal of Infectious Diseases, 179:367–70
11. Chen,HL., Chang,MH., Ni,YH., Hsu,HY., Lee,PL., Lee,CY., Chen, DS. (1996) “Seroepidemiology of hepatitis B virus infection in children: ten years of mass vaccination in Taiwan” JAMA, 276:906–8.
12. Lee,CL., Hsieh,KS., and Ko,YC. (2003)“ Trends in the Incidence of Hepatocellular Carcinoma in Boys and Girls in Taiwan after Large-Scale Hepatitis B Vaccination” Cancer Epidemiology, Biomarkers & Prevention, 12:57-59
13. Lu,SQ., Sarah M. McGhee, Xu Xie, Cheng Jinquan, Richard Fielding (2013) “Economic evaluation of universal newborn hepatitis B vaccination in China” Vaccine 31: 1864–1869
14. Yang,BM., Paik,SW. Hahn,OS., Yi,DH., Choi,MS., and Sarah Payne “Economic evaluation of the social costs of hepatitis B in South Korea” (2001) Journal of Gastroenterology and Hepatology, 16: 301-308
15. Carolina Barbosa, Emily A. Smith, Thomas J. Hoerger, Nancy Fenlon, Sarah F. Schillie, Christina Bradley and Trudy V. Murphy, “ Cost-effectiveness Analysis of the National Perinatal, Hepatitis B Prevention Program”(2014) Official journal of the American Academy of Pediatrics, 133(2): 243-253
16. Bloom, Bernard S., Alan L. Hillman, Mark A. Fendrick “A Reappraisal of Hepatitis B Virus Vaccination Strategies Using Cost-Effectiveness Analysis”(1993) Annals of Internal Medicine, 18(4): 298-306
17. Huang,KY., Lin,SR. (2000)“Nationwide vaccination: A success story in Taiwan”, Vaccine 18 (2000): S35-S38
18. Croagh,Catherine MN., John S. Lubel. (2014)“ Natural history of chronic hepatitis B: Phases in a complex Relationship”, World Journal of Gastroenterol, 20(30): 10395-10404
19. Nguyen,T., Alexander J.V. Thompson ,Scott Bowden, Catherine Croagh, Sally Bell ,Paul V. Desmond, Miriam Levy, Stephen A. Locarnini (2010)“Hepatitis B surface antigen levels during the natural history of chronic hepatitis B: A perspective on Asia” Journal of Hepatology, 52: 508–513
20. Jaroszewicz, Jerzy, Beatriz Calle Serrano, Karsten Wursthorn, Katja Deterding, Jerome Schlue, Regina Raupach, Robert Flisiak, C.-Thomas Bock, Michael P. Manns, Heiner Wedemeyer, Markus Cornberg.(2010) “Hepatitis B surface antigen (HBsAg) levels in the natural history of hepatitis B virus (HBV)-infection: A European perspective” Journal of Hepatology, 52: 514–522
21. Liaw, YF., Chu, CM. (2009) “Hepatitis B virus infection” Lancet , 373 : 582–92
22. Thistlethwaite, Donald L., and Donald T. Cambell. (1960) “Regression -Discontinuity Analysis: An Alternative to the Ex Post Facto Experiment.” Journal of Educational Psychology, 51(6): 309-17.
23. Lee, David S. and Thomas Lemieux (2010) “Regression Discontinuity Designs in Economics”, Journal of Economic Literature, 48(2): 281-355
24. Imbens, Guido , and Karthik, Kalyanaraman (2012) “Optimal Bandwidth Choice for the Regression Discontinuity Estimator”, Review of Economic Studies: 1-27
25. Griliches, Zvi and William M. Mason (2013) “Education, Income, and Ability”, Journal of Political Economy, 80(3): S74-S103